Abstract
- The 48 Channel Mono / 16 Channel RGB LED Controller by Chromation Systems can be used to independantly control 48 groups/channels (up to 120ma per group) of mono-color LEDs or 16 groups/channels of common anode RGB LEDs. It utilizes 3x TLC5940 LED drivers controlled with a PIC 18F2550 microcontroller.
- Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells. Therizols P, Illingworth RS, Courilleau C, Boyle S, Wood AJ, Bickmore WA Science, 346(6214):1238-1242, 01 Dec 2014.
- Profiles of DNA methylation of many tissues relevant in human disease have been obtained from microarrays and are publicly available. These can be used to generate maps of chromatin compartmentalization, demarcating open and closed chromatin across the genome. Additionally, large sets of genome-wide transcription factor binding profiles have been made available thanks to ChIP-seq technology.
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Sequence reads for pediatric GBM samples for manuscript: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma.
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Understanding of the diverse role of the human long non-coding RNAs (lncRNAs) is a considerable emerging field in development and disease (1). LncRNAs are broadly defined as noncoding RNAs longer than 200 nucleotides, separating them from various classes of microRNAs (miRNAs), small nuclear RNAs (snRANs), and small nucleolar RNAs (snoRNAs) that function through distinct mechanisms (2,3). The majority of lncRNAs are transcribed by RNA polymerase II (RNAP2), hence sharing similarities with messenger RNAs (mRNAs).